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Vasotec (Enalapril)

Vasotec (Enalapril) is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. Enalapril is commonly used for the following conditions to lower high blood pressure (hypertension).

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Vasotec (Enalapril) is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. Enalapril is commonly used for the following conditions to lower high blood pressure (hypertension). Enalapril blocks the angiotensin-converting enzyme (ACE) from forming a hormone called angiotensin II. When angiotensin II binds to receptors, it causes your blood vessls to constrict. Blocking the formation of angiotensin II helps your blood vessels relax so that blood can move through them more easily. These effects can help your heart work better, lower blood pressure, and may reduce your risk for heart attack and stroke. 

Side Effects:

The most common side effects of enalapril are listed below. Tell your healthcare provider if you have any of these side effects that bother you.

  • Tiredness
  • Low blood pressure (see below)
  • Dizziness
  • Cough

There may be other side effects of enalapril that are not listed here. Contact your healthcare provider if you think you are having a side effect of a medicine. 

While less common, the most serious side effects of enalapril are described below, along with what to do if they happen.

Angioedema. Enalapril may cause a rare reaction called angioedema. The usual symptoms of this reaction include swelling of the lips, face, tongue, or throat. Stop using the medicine and contact your healthcare provider if you have this type of swelling. If you are having trouble breathing, get medical attention right away.

Low Blood Pressure (Hypotension). Enalapril may cause low blood pressure. Low blood pressure is more likely to occur if you have excessive sweating or persistent or severe vomiting or diarrhea. If you feel faint or dizzy, lie down. Tell your healthcare provider right away if you have any of the following symptoms of low blood pressure.

Warnings & Precautions:

Allergies to Ingredients. People who are allergic to any of the following should not take enalapril.

Your pharmacist can tell you all of the ingredients in the specific enalapril products they stock.

History of Angioedema. Enalapril may cause a rare reaction called angioedema, where there is swelling under the skin. This medicine should not be used if you have had angioedema. 

Drug Interactions. Enalapril should not be taken while you are using certain other medicines. Before taking enalapril, tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.  See the Interactions section for more details.

Interactions:

Does enalapril interact with foods or drinks?

There are no known interactions between enalapril and foods or drinks. It is unknown if drinking alcohol will affect enalapril. The risk of dizziness may be increased if you drink alcohol while taking enalapril.

Does enalapril interact with other medicines (drug interactions)?

Always tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.

In particular, make sure that you discuss if you are using any of the following before taking enalapril.

  • Aliskiren (Tekturna), which is a medicine for high blood pressure
  • Entresto (sacubitril/valsartan), which is a medicine for heart failure 
  • A supplement or salt-substitute containing potassium
  • A diuretic, also called a water pill, which is a medicine used to reduce edema (fluid retention) and blood pressure
  • A nonsteroidal anti-inflammatory drug (NSAID), such as ibuprofen, naproxen, and others, which are contained in many prescription and OTC products for pain, swelling, and fever
  • Lithium, which is a medicine for certain mental health conditions
  • An angiotensin-converting enzyme (ACE) inhibitor, which is a medicine for high blood pressure, heart failure, and certain kidney problems
  • An angiotensin II receptor blocker (ARB), which is a medicine for high blood pressure, heart failure, and other heart conditions
  • A medicine such as everolimus (Afinitor, Zortress), sirolimus (Rapamune and others), or temsirolimus (Torisel), which is commonly used to treat cancer or after an organ transplant
  • Any medicine for high blood pressure

This may not be a complete list of medicines that can interact with enalapril. Always check with your healthcare provider.

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